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A no-nonsense chemist becomes a TV cooking-show sensation in the new novel "Lessons in Chemistry." Scott Simon talks with author Bonnie Garmus about her book.

California hospitals are mandated to be safe in the event of a major earthquake. The institutions most vulnerable to quake damage are the state's small, rural hospitals. But many say the cost of seismic retrofitting is too expensive. Cy Musiker of member station KQED reports.

Commentator Melissa Fay Greene is an author and the mother of adopted children from Africa. She tells the story of two AIDS orphans, who are now part of her family.

Sony's Playstation 3 is in hot demand and short supply this weekend. And to make it an official video gamer weekend, on Sunday, Nintendo releases its coveted Wii gaming system. Weekend Edition's Andrea Seabrook tried out Nintendo's latest game box the Wii in NPR's studio with Ralph Cooper and Kyle Orland the co-hosts of NPR's video-game podcast "Press Start."

Prime Minister Ariel Sharon fought for his life Thursday following seven hours of emergency surgery to stop widespread bleeding in his brain. The massive stroke made it unlikely that he would return to power.

The Senate Judiciary Committee has approved a plan that would give the nearly 12 million undocumented workers now living in the United States a path to citizenship. The debate now moves to the full Senate. NPR's Jennifer Ludden helps explain the politics and policies involved.

NPR must lay off 10% of its workforce to address an advertising shortfall of about $30 million, CEO John Lansing says. Lansing says marketers are nervous about the economy.

Nearly two million gallons of wastewater and thousands of cubic yards of contaminated soil have already been removed from the site, with more to go. Every aspect of removal is governed by regulations.

A recent podcast series digs into the beginnings of conservative talk radio and tracks its rise. NPR's Steve Inskeep talks to Katie Thornton, the host of "The Divided Dial."

Love them or hate them, we can't resist "best of" lists. But why?